In LOAD2 mice on a high-fat diet, synapses go haywire even without Aβ plaques. ApoE-Christchurch variant bolsters protective ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

Using engineered mice, researchers developed monoclonal antibodies that were effective against infection with A. baumannii.

Authors show that CD206-targeted antigens access both exogenous and cross-presentation pathways, as evidenced by proliferation of splenocytes from the transgenic mice. In parallel, the study also ...

Monoclonal antibodies—treatments developed by cloning a cell that makes an antibody—could help provide an answer to the ...

America's COVID celebrity is facing scrutiny for funding risky research that may have sparked the pandemic—and for allegedly ...

"We started with a recombinant mouse antibody. Our challenge was to develop a humanized form of this antibody that could achieve the same effect as that achieved in mice models and be safely used ...

Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists.