Stem cells can tailor their role in gene therapy based on the underlying disease, study suggests
RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying genetic ...
Nature5y
Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells
You have full access to this article via your institution. Figure 1: Presentation of gene trap vectors and integration sites. We generated approximately 12,000 targeted ES cell lines using both ...