Representational Photo The exploration of novel peptides for their potential impact on metabolic pathways has been a ...

BACKGROUND: The docking protein IRS2 (insulin receptor substrate protein-2) is an important mediator of insulin signaling and ...

Semaglutide injections effectively support weight loss by regulating appetite and glucose levels, offering benefits for ...

A UCLA-led research team has found that a gene mutation that affects insulin signaling in the heart may raise the risk of deadly abnormal heart rhythms in a subset of patients with cancer and could ...

An experimental weight-loss pill helped people drop 13% of their body weight in a three-month period. The results from early ...

This is the first time that this signaling pathway (GAS6 and AXL) has been directly implicated in insulin resistance. This work also suggests that GAS6 or its receptor AXL could be therapeutic ...

Our previous studies have shown that ProINS-Tf was converted to active insulin-transferrin (INS-Tf) via the transferrin (Tf)-receptor–mediated pathway in hepatoma cells. We hypothesized that ...

Obesity, a persistent metabolic state characterized by an excess accumulation of adipose tissue, has emerged as a global ...

Why insulin ... receptor from its downstream effectors, effectively terminating insulin signal transduction. In short, this means that insulin resistance can disrupt the normal signaling pathways ...

Half a century of advancements in biomedical science paved the way for today’s powerful weight-loss drugs like Ozempic — so ...

Half a century of advancements in biomedical science paved the way for today's powerful weight-loss drugs like Ozempic -- so ...

"Amycretin is the first treatment to harness the two distinct biological pathways stimulated by amylin ... that plays a crucial role in regulating insulin and hunger signals, amplifies this ...