Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable ...

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. According to their new ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...

Super-immunodeficient mice as well as advanced humanized models have enabled a deeper understanding of disease mechanisms and accelerated the development of novel therapeutics that have a greater ...

Kobe University immuno-oncologist SAITO Yasuyuki and his team developed a mouse model with a humanized immune system. With this they successfully tested a new therapeutic approach in which immune ...

More information: Carla Panisello et al, NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid–lymphoid representation with limited graft-versus-host ...

Editas Medicine Inc. has achieved in vivo preclinical proof of concept of hematopoietic stem and progenitor cell (HSPC) ...

Editas Medicine Announces Progress Towards 2024 Goals, Including Achievement of In Vivo Preclinical Proof of Concept and ...

The human CD206 molecule was first incorporated in mice by microinjection of hu CD206 gene expressed under the control of its own promoter, into fertilized oocytes from C57BL/6 mice. The ...

Already, these new mouse models have helped scientists capture a clearer picture of how SARS-CoV-2 affects humans. They are ...