The departures leave just one sitting member of the board, its chair, Anne Wojcicki, who co-founded the genetics-testing company in 2006 and serves as its chief executive officer.

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helen89—Getty Images At around 7 a.m. on a Friday, Denise Prudhomme scanned into her Wells Fargo job, housed in a corporate office in Tempe, Ariz. She was found dead in her cubicle four days later.

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The history of the DNA-testing startup reads like a checklist of Silicon Valley clichés: founder squabbles, gobs of cash, a ...