This is the first time that this signaling pathway (GAS6 and AXL) has been directly implicated in insulin resistance. This ...

BACKGROUND: The docking protein IRS2 (insulin receptor substrate protein-2) is an important mediator of insulin signaling and ...

Introduction ADVERTISEMENT Peptides have become a focal point in research due to their intricate interactions with metabolic ...

Dopamine receptors bind dopamine, insulin receptors bind insulin ... a sequence of molecular switches to internal signaling pathways. Membrane receptors fall into three major classes: G-protein ...

Semaglutide injections effectively support weight loss by regulating appetite and glucose levels, offering benefits for ...

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical ...

For experiments investigating post-transcriptional regulation, I use the Drosophila insulin-like receptor pathway and the cellular response to insulin. Transcriptional control of gene expression The ...

Our previous studies have shown that ProINS-Tf was converted to active insulin-transferrin (INS-Tf) via the transferrin (Tf)-receptor–mediated pathway in hepatoma cells. We hypothesized that ...

An experimental weight-loss pill helped people drop 13% of their body weight in a three-month period. The results from early ...

G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.

Why insulin ... receptor from its downstream effectors, effectively terminating insulin signal transduction. In short, this means that insulin resistance can disrupt the normal signaling pathways ...