Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include ...

To achieve this goal of glucose responsiveness, the researchers introduced an ‘on/off switch’ into the insulin molecule. Under high glucose conditions, the switch on their modified insulin ...

Dysfunctions of the tiny cell processes (primary cilia*) of the pancreatic beta cells could be a cause of type 2 diabetes.

In the latest study, the insulin molecule itself has been made sensitive ... The NNC2215 molecule consists of two major parts ...

a ring-shaped structure known as a macrocycle and a glucoside, a molecule derived from glucose. When blood-glucose concentrations are low, the glucoside binds to the ring, keeping the insulin in a ...

Researcher Rita Slaaby and colleagues present a modified form of insulin with activity that varies according to the levels of glucose in the blood. The molecule, named NNC2215, is equipped with a ...

How quickly a shot of insulin is absorbed into the blood depends upon where the injection is given. And while researchers have made innovative chemical modifications to insulin formulations ...

It is the last bullet point that’s creating issues. During the 2023 Open Enrollment Period, I discovered that some clients’ insulin would not be covered by their plans in the new year.

He also points out that engineered insulin may cause an immune response and that NNC2215’s complex synthesis might be expensive. Andy Chapman, CEO of the molecular recognition company ...

Some diabetes patients this year have had trouble finding their preferred insulin brands as major drug manufacturers reported shortages of the medicine. USA TODAY set out to find out what patients ...

Janel Wright had just days left in her insulin supply in early January when a pharmacist told her there was none of the drug left to fill her prescription. Her neighborhood Fred Meyer pharmacy in ...